Yes. From Ryding and Pechefsky: "One symphony that Walter had avoided through the years was Mahler’s Sixth. The deepest reasons for his avoidance of this powerful work—notwithstanding his statement that the symphony is “bleakly pessimistic” and “ends in hopelessness”—are ultimately shrouded in mystery, yet he claimed to be delighted that Mitropoulos was scheduling the work."

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I think I read somewhere years ago - but I can't recall the source - that Walter never conducted the Sixth because he fud it too dark