Common challenges include module compatibility issues, data mapping errors, and UI changes. Custom modules from older versions might not be supported in the new version, requiring redevelopment. Also, third-party integrations may need updates. Businesses often overlook testing, which leads to post-migration errors. Working with skilled Odoo developers reduces these risks. Proper planning, code review, and test environments help address issues early, making migration successful and disruption-free for your business operations.